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Table of Contents

- History of Grape Seed Extract -
- Fast Facts -
- Health & Beauty Benefits -
- Skin Benefits -
- Grape Seed Extracts for Skincare -
- Ebanel Products with Grape Seed Extract -

A report by the University of Maryland Medical Center shows that Grapes have been used since ages to treat a variety of conditions related to the skin. Grape vine leaves were used to get rid of pain and inflammation, and the unripe grapes were used to soothe painful sore throats. The grape seeds are even more useful and are used to produce Grape Seed Extract.

Grape Seed Extract comes with a plethora of medicinal and skin care benefits, and is found in capsule, liquid, and tablet forms. People around the world apply Grape Seed Extract topically to keep their skin smooth, shining, and nourished. In this guide, we’ll discuss Grape Seed Extract (also known as Vitis Vinifera (Grape) Callus Culture Extract) in detail. Keep reading to know more.

History & Traditional Uses of Grape Seed Extract

There’s a long history of medical and skin benefits related to grapes. 

The Grape Seed Extract was first produced in 1970. It was extracted from the crushed seeds of the grape plants.

Grape Seed Extract contains proanthocyanidin, a phenolic chemical and a member of the plant phytochemical family or flavonoids. Oligomeric proanthocyanidin (OPC) is also an antioxidant which has been studied since ages for its potential health benefits.

As on date, Grape Seed Extract is being used as a dietary supplement for different conditions such as insufficiency of the venous system (when the veins are unable to send blood from the legs to the heart), inflammation, wound healing, etc. 

Most of the research on Grape Seed Extract was performed in Europe. A 2003 study also reveals that Grape Seed Extract can effectively replace estrogen and reduce hypertension in postmenopausal women.


Grape Seed Extract – Fast Facts

Let’s look at some interesting facts about Grape Seed Extract before we move on to the health and skin benefits.

  • Some studies reveal that the chemical compounds present in Grape Seed Extract can reduce swelling and alleviate symptoms of venous insufficiency.
  • The National Center for Complementary and Integrative Health (NCCIH) is conducting research on Grape Seed Extract for its ability to treat Alzheimer’s disease and genetic hemochromatosis (a condition where there is excess iron in the body).
  • The National Cancer Institute is conducting research on Grape Seed Extract for preventing lung, color, and prostate cancer.
  • Grape Seed Extract does not cause any side effects.
  • Do not use Grape Seed Extract if you are suffering from a bleeding disorder or are consuming anticoagulants.
  • Grape Seed Extract has powerful antioxidant and free radical elimination properties.
  • 70% to 90% of Grape Seed Extract contains Proanthocyanidin.

Grape Seed Extract is made of bitter-tasting seeds of grapes that are removed, dried, and pulverized to produce the extract.






Health & Beauty Benefits of Grape Seed Extract

Grape Seed Extract is one of the largest reservoirs of Proanthocyanidins. Also, the extract is rich in other antioxidants such as flavonoids, phenolic acids, and anthocyanins. All these properties of Grape Seed Extract come together to provide several health and skin benefits.

Health benefits of Grape Seed Extract

Let’s first look at some of the primary health benefits of Grape Seed Extract.

Grape Seed Extract can reduce oxidative damage

Grape Seed Extract supplements help in lowering LDL cholesterol levels. A study conducted on 8 healthy people who consumed high-fat meals, 300 mg of Grape Seed Extract prevented the oxidation of fats in the blood. In the case of people who were not administered Grape Seed Extract, 150% increase in fat was observed.


Grape Seed Extract can improve bone strength and collagen

The increased consumption of flavonoid is directly related to the formation of bones and synthesis of collagen. Since Grape Seed Extract is rich in flavonoids, it can help you increase bone strength and density. Research shows that adding Grape Seed Extract to a low or medium-calcium diet can improve mineral content, bone density, and bone strength. Grape Seed Extract is also beneficial for patients suffering from the autoimmune condition Rheumatoid Arthritis.


Grape Seed Extract can better kidney function

Human kidneys are highly prone to irreversible oxidative damage. Studies conducted in animals show that Grape Seed Extract can lower kidney damage and improve kidney function. A study performed on 23 people suffering from chronic renal failure were administered 2 g of Grape Seed Extract every day for almost 6 months, and the results were analyzed against a group of patients who were not administered Grape Seed Extract. In patients consuming Grape Seed Extract daily, kidney function improved by 9% and urinary protein reduced by 3%.


Grape Seed Extract can prevent infections

Grape Seed Extract has antifungal and antibacterial properties. Research shows that Grape Seed Extract helps in preventing the growth of foodborne bacterial infections such as E.Coli, Campylobacter, and Shiga Toxins. All these bacteria are responsible for upset stomach and food poisoning. During the lab test, Grape Seed Extract was found to control the growth of 43 different antibiotic-resistant strains of Staphylococcus aureus bacteria.


Grape Seed Extract can reduce the risk of cancer

Increased intake of flavonoids is linked with a reduced risk of different types of cancers. The strong antioxidants effects of Grape Seed Extract can prevent lung cancer, gastric cancer, breast cancer, pancreatic cancer, oral squamous cell cancer, and liver cancer. Studies conducted on animals have revealed that Grape Seed Extract can boost the effects of various types of chemotherapy.


Beauty benefits of Grape Seed Extract

Grape Seed Extract is an excellent source of Vitamin C, Vitamin E, flavonoids, and antioxidants. All these chemical compounds come together to improve the texture of the skin and minimize the signs of aging. Grape Seed Extract is popular for its anti-aging effects. Moreover, its ability to kill free radicals and guard the skin makes it one of the main ingredients in several cosmetics. It is also used for healing cuts and wounds.

Skin Benefits of Grape Seed Extract 

Grape Seed Extract comes with anti-aging properties


As you continue to grow old, your skin loses its sheen and elasticity, and begins to display signs of aging. These include age spots, wrinkles, sagging skin, and fine lines. Along with growing age, other factors that can lead to aging are exposure to UV rays and toxins in the environment. Grape Seed Extract contains tiny molecules that get easily absorbed in the skin. Antioxidants present in Grape Seed Extract, especially Vitamin C, can reduce wrinkles and fine lines. A study conducted at the St. Helena Institute of Plastic Surgery revealed that people using Grape Seed Extract serum on their skin for 6 weeks noticed 88% improvement in skin texture.


Grape Seed Extract neutralizes harmful free radicals that can damage the skin

Grape Seed Extract can kill free radicals and prevent skin damage. You’ll be surprised to know that Grape Seed Extract is a powerful antioxidant. It is 50 times more potent than Vitamin E. Grape Seed Extract doesn’t just guard the skin cells from free radicals; it scans the entire body to gather free radicals and eliminate them. The anti-free radical effect of Grape seed Extract was discovered by Professor Masqueller in 1986. Another study revealed that Grape Seed Extract guards the skin cells against toxic effects of oxidative stressors. By eliminating free radicals, Grape Seed Extract prevents the appearance of fine lines and wrinkles.

Grape Seed Extract protects the skin against sun damage and sunburn

Grape Seed Extract comprises resveratrol and proanthocyanidins, along with many other powerful antioxidants. Scientific studies reveal that when Grape Seed Extract is applied to the skin before exposure to UV rays, it acts as a potential sunscreen and reduces skin redness and burns. A study published by Nutrition and Cancer journal claims that topical application of Grape Seed Extract can prevent skin cancer. Please note that Grape Seed Extract cannot be used as an alternative for sunscreen. It simply adds an additional layer of protection against harmful UV rays.


Grape Seed Extract boosts skin hydration

Research shows that people consuming Grape Seed Extract in oral form as well as topical form showed improved skin hydration levels.



Grape Seed Extract smoothens and softens skin

Grape Seed Extract also acts as a moisturizing agent. It is used by several massage therapists across the world. Vitamin E present in Grape Seed Extract penetrates into the skin membrane and helps retain moisture.



Grape Seed Extract helps in healing and calming the skin

Grape Seed Extract contains Alpha Hydroxyl Acid that helps a great deal in healing wounds and cuts. Alpha Hydroxyl Acid helps the skin cells hold moisture and minimizes scarring. This leads to faster healing of wounds. Grape Seed Extract also helps in treating eczema and psoriasis. The elastin and collagen inside the skin keep it healthy. Proanthocyanidins block enzymes that disturb the chemical structure of elastin and collagen.

Grape Seed Extract also acts as an anti-inflammatory natural remedy and can be used for treating swelling caused by infections, dermatitis, cuts, and UV ray exposure.


    Grape Seed Extract skincare products you can use

    If you’re planning to use Grape Seed Extract for your skin, you can use this effective ingredient in the following forms:

    1. Moisturizer

    Many leading skin care brands and dermatologists have added Grape Seed Extract to moisturizing skin creams to provide you with smooth, shiny, and nourished skin. Grape Seed Extract moisturizer lightens the skin and hydrates it. Vitamin C and Vitamin E present in Grape Seed Extract reduce skin damage and environmental stress.

    2. Oil & Serums

    A powerful combination of Grape Seed Oil and Almond Oil can be used to improve skin radiance, prevent fine lines and wrinkles, and enhance the luminosity of your skin.

    3. Mask

    Grape Seed Extract can team up with other effective skin care ingredients such as Liquorice Extract to calm your skin, soothe it, and provide antioxidative support. You may also find Grape Seed Extract and Bentonite mask that can help unclog skin pores and detoxify your skin.

    Grape Seed Extract is completely safe and natural.


    Ebanel Products with Grape Seed Extract

    Liposomal Retinol Peptide SerumLiposomal Retinol MoisturizerMagnetic Dead Sea Mud Mask