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Ebanel®

Numb 520 Cream

$ 17.69

Numb 520 is Ebanel's maximum strength 5% lidocaine numbing cream, formulated with liposomal technology for fast-acting, deep-penetrating relief. It begins working within 3 to 5 minutes, peaks at 20 to 25 minutes, and lasts approximately one hour from peak.

The water-based, oil-free formula absorbs cleanly with no greasy residue. It contains allantoin and vitamin E to support skin comfort during and after application. Non-addictive, hypoallergenic, and odor-free.

Manufactured in the United States at an FDA-registered, cGMP-compliant facility. FSA and HSA eligible.

Uses

  • For the temporary relief of local and anorectal itching and discomfort associated with anorectal disorders and anorectal inflammation.
  • For the temporary relief of:
    • Pain
    • Burning
    • Soreness

Directions

Adults:

  • When practical, cleanse the affected area with mild soap and warm water and rinse thoroughly.
  • Gently dry by patting or blotting with toilet tissue or a soft cloth before application of this product.

Children under 12 years of age: consult a doctor.

Apply externally to the affected area up to 6 times daily.

Ingredients

Active Ingredient: 

Lidocaine 5% - Local Anesthetic

Inactive Ingredients: Allantoin, Aloe Barbadensis Leaf Juice, Benzyl Alcohol, Carbomer, Cholesterol, Dimethyl Isosorbide, Disodium EDTA, Hydrogenated Polydecene, Lecithin, Neopentyl Glycol Dicaprylate/Dicaprate, Propylene Glycol, Sodium Polyacrylate, Tocopheryl Acetate, Trideceth-6, Triethanolamine, Water

Warnings

  • If condition worsens or does not improve within 7 days, consult a doctor.
  • Do not exceed the recommended daily dosage unless directed by a doctor.
  • In case of bleeding, consult a doctor promptly.
  • Do not put this product into the rectum by using fingers or any mechanical device or applicator.
  • Certain persons can develop allergic reactions to ingredients in this product. If the symptom being treated does not subside or if redness, irritation, swelling, pain, or other symptoms develop or increase, discontinue use and consult a doctor.

Other Information

  • Keep away from direct sunlight or heat
  • Store at room temperature 15°-30°C (59°-86°F)
  • This package is child-resistant. Keep out of reach of children
  • In case of accidental overdose or ingestion, call a doctor or poison control center immediately
  • Do not use this product if seal is broken or missing

How It Works

How It Works Numb 520 delivers lidocaine, an FDA-recognized local anesthetic, directly to perianal nerve endings, temporarily blocking pain signal transmission. The result is fast, measurable relief from discomfort, itching, burning, and soreness associated with anorectal disorders. Liposomal Delivery Standard topical anesthetics sit on the skin surface. Numb 520 uses liposomal encapsulation, lipid-based spheres that mirror cell membrane structure, to carry lidocaine deeper into tissue and release it gradually. This improves both onset speed and sustained effect duration compared to non-encapsulated formulations. Onset and Duration Onset (3-5 minutes): Lidocaine begins blocking sodium channels in perianal nerve endings. Peak Effect (20-25 minutes): Maximum numbing depth via liposomal delivery. Duration (approximately 1 hour from peak): Effect tapers as lidocaine clears from tissue. Formula The water-based, oil-free base absorbs without greasy residue. Allantoin: Supports skin comfort and helps soothe the perianal area during and after application. Vitamin E: Antioxidant support that helps condition skin at the application site. Non-addictive. Hypoallergenic. Odor-free.

Numb 520 FAQs

What is the strongest lidocaine cream available without a prescription?
5% lidocaine is the highest concentration permitted OTC in the United States. Numb 520 contains 5% lidocaine, the maximum strength available without a prescription, delivered via a liposomal base for enhanced absorption.

How long does Numb520 take to work?
Onset begins within 3 to 5 minutes of application. Peak numbing effect is reached at 20 to 25 minutes and lasts approximately one hour from peak. Results vary based on skin thickness and individual metabolism.

How often can I apply Numb 520?
Adults may apply up to 6 times daily as directed. Do not exceed the recommended dosage unless directed by a physician. Children under 12 should consult a doctor before use.

Is Numb 520 FSA or HSA eligible?
Yes. Numb520 is an FDA-regulated OTC drug product and is eligible for FSA and HSA accounts.

What makes Numb 520 different from other lidocaine creams?
Numb 520 uses liposomal technology. Liposomes are microscopic lipid vesicles structurally similar to cell membranes, which supports faster, more consistent absorption of lidocaine into the treatment area. The formula is oil-free, odor-free, non-greasy, and water-based.

Where is Numb 520 manufactured?
Manufactured in the United States at an FDA-registered, cGMP-compliant facility by Ebanel, a Small, Minority, and Women-Owned Business based in Brea, California.


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